Surrogacy assessment using principal stratification when surrogate and outcome measures are multivariate normal
نویسندگان
چکیده
منابع مشابه
Surrogacy assessment using principal stratification when surrogate and outcome measures are multivariate normal.
In clinical trials, a surrogate outcome variable (S) can be measured before the outcome of interest (T) and may provide early information regarding the treatment (Z) effect on T. Using the principal surrogacy framework introduced by Frangakis and Rubin (2002. Principal stratification in causal inference. Biometrics 58, 21-29), we consider an approach that has a causal interpretation and develop...
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ژورنال
عنوان ژورنال: Biostatistics
سال: 2013
ISSN: 1465-4644,1468-4357
DOI: 10.1093/biostatistics/kxt051